2.10 Effect of pH on the rate of reaction

 Understand how the functioning of enzymes can be affected by changes in pH

1. Lower PH (acidic) = the rate of reaction gradually decreases. 
Optimum PH = maximum rate = rate of reaction decreases. 
Higher Ph (alkaline conditions) = rate of reaction gradually decreses. 

Graph is more symmetrical. 

Acidic and Alkaline conditions change the shape of the ACTIVE SITE and this slows the reaction.